Pancreatic Cancer :: Cytokeratin 20 Expression Linked to Poor Survival

According to an early on-line article published in the journal Cancer, strong expression of the protein cytokeratin 20 in pancreatic cancer is associated with significantly worse survival than low levels or no expression of cytokeratin 20. Patients diagnosed with pancreatic cancer who have a strong cytokeratin 20 expression may wish to undergo more aggressive therapy or participate in a clinical trial to improve their outcomes.

Lymphoma :: BiovaxID – Promising for Follicular Lymphoma

According to results recently presented at the 47th annual meeting of the American Society of Hematology (ASH), the vaccine BiovaxID, which is still in clinical trials, appears very promising in the treatment of follicular lymphoma.

Leukemia :: GX15-070 Active in Refractory CLL

According to results recently presented at the 47th annual meeting of the American Society of Hematology (ASH), the agent GX15-070, which is still in clinical trials, has anticancer activity in patients with chronic lymphocytic leukemia (CLL) who have stopped responding to standard therapies including chemotherapy, Rituxan?, and Campath?.

Leukemia :: Older AML patients do not benefit from more therapy

According to results presented at the 47th annual meeting of the American Society of Hematology (ASH), patients 60 years of age and over diagnosed with acute myeloid leukemia (AML) do not benefit from increased doses of the commonly used chemotherapy agents daunorubicin (Cerubidine?) or cytarabine (Cytosar-U?); as well, increasing the number of treatment courses of subsequent chemotherapy does not provide benefit.

Lymphoma :: Autoimmune diseases linked with Non-Hodgkin’s Lymphoma

According to a study published in the Journal of the National Cancer Institute, the risk of diffuse large B-cell lymphoma (a subtype of non-Hodgkin’s lymphoma) is elevated among patients with rheumatoid arthritis, Sj?gren syndrome, systemic lupus erythematosus, or celiac disease. Some of these conditions were also linked with marginal zone lymphoma, lymphoplasmacytic lymphoma, and T-cell lymphoma.

Heart Disease :: Having a Sibling with Heart Disease

Having a sibling with a history of cardiovascular disease carries the same or greater risk as having a parent with a history of the disease, according to a new report from the long-standing Framingham Heart Study conducted by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health (NIH). Personal risk of having a cardiovascular event, such as a heart attack, stroke, or peripheral artery disease, may be raised by as much as 45 percent in middle-aged people whose brother or sister has had such an event.

Diabetes :: Strict blood sugar control cuts diabetes heart risk

A 20-year study of people with type 1 diabetes shows that tight control of blood sugar levels cuts their risk of heart disease by more than half. The new research, published in the Dec. 22 New England Journal of Medicine, is “a landmark study,” according to Dr. William T.

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