Inflammation | Page 15 of 58

Alzheimer’s Disease :: Paving the way toward a vaccine against Alzheimer’s disease

Scientists have provided new details about how proteins used to destroy bacteria and viruses may help treat Alzheimer?s disease. Gunnar K. Gouras, associate professor of neurology and neuroscience at Weill Medical College of Cornell University, New York, and colleagues provide new insights into how these proteins, called antibodies, reduce the main hallmarks of Alzheimer?s disease and raise hopes for a vaccine against the disease.

Frostbite :: Clot-dissolving agent may be beneficial in treatment of severe frostbite

A preliminary study suggests that a blood clot-dissolving medication that is administered to some patients following a stroke or heart attack may help to reduce the risk of amputation following severe frostbite, according to a report in the June issue of Archives of Surgery, one of the JAMA/Archives journals.

Brain :: Blood-brain barrier breached by new therapeutic strategy

A major obstacle in the treatment of infections and other diseases of the brain is the blood-brain barrier, which prevents systemically delivered therapeutic drugs from reaching the brain.

Inflammation :: Inflammation is at the origin and progression of diseases such as diabetes or cancer

Fifteen top international specialists in this field will gather from 25-27 June for a conference entitled, ?Inflammation and Chronic Disease?, part of the ?Barcelona BioMed? conference series organised by the Institute for Research in Biomedicine (IRB Barcelona) and the Fundaci?n BBVA.

Smallpox :: Fever after smallpox vaccination tied to individual genetic variations

St. Louis researchers have identified common DNA variations that underlie susceptibility to fever after smallpox vaccination. Their finding is the first to link individual differences written into the genetic code with a vaccine-related complication ? albeit a mild one.

Rheumatoid Arthritis :: Roche’s Actemra improves rheumatoid arthritis symptoms

Results of the Option (TOcilizumab Pivotal Trial in Methotrexate Inadequate respONders) trial, the first multinational Phase III study outside of Japan, showed that patients treated with Actemra (either 4mg/kg or 8mg/kg) plus methotrexate achieved a significant and clinically important improvement in the signs and symptoms of moderate to severe rheumatoid arthritis (RA) compared to patients treated with placebo and methotrexate, a current standard of care.

Dental :: Gum disease in postmenopausal women linked to oral bone loss

A study conducted in a large sample of postmenopausal women by University at Buffalo epidemiologists has provided new information on the prevalence of certain gum-disease-causing oral bacteria in this population and the association of the bacteria with oral bone loss.

Rheumatoid Arthritis :: Smoking, low levels of education and glucose tolerance increase risk of rheumatoid arthritis

New data presented today at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain, sheds light on the role of environmental and genetic risk factors in the development of rheumatoid arthritis (RA).

COPD :: Premature vascular and bone changes occur in COPD patients

Researchers in the United Kingdom have found that patients with COPD, or chronic obstructive pulmonary disease, have greater arterial stiffness. The researchers also found that those COPD patients with osteoporosis, a common complication of the respiratory disease, had even greater arterial stiffness. These premature signs of aging may explain why COPD patients are at greater risk for cardiovascular disease.

Ankylosing Spondylitis :: Remicade in ankylosing spondylitis show improvement in spinal mobility & spinal inflammation

Data presented today at the European League Against Rheumatism (EULAR) Annual European Congress of Rheumatology showed that patients with ankylosing spondylitis (AS) who received REMICADE? (infliximab) over two years experienced significant improvement in spinal mobility.