Crohn’s Disease :: Remicade – Treatment for Pediatric Crohn’s Disease

Centocor, Inc. and Schering-Plough Corporation (NYSE: SGP) announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) issued a positive opinion recommending the approval of REMICADE(R) (infliximab) for the treatment of severe, active Crohn’s disease (CD) in pediatric patients aged 6 to 17 years, who have not responded to conventional therapy including a corticosteroid, an immunomodulator and primary nutrition therapy, or who are intolerant to, or have contraindications for, such therapies.

Kidney Cancer :: Sutent achieves first line EAU approval for kidney cancer

Sutent (sunitinib malate) has received a European Association of Urology recommendation, as first-line therapy in patients with metastatic renal cell carcinoma of good and intermediate risk, just two months after gaining EU marketing authorization for first line use in all patients with advanced and/or metastatic renal cell carcinoma.

Pediatrics :: Most children in US hospitals receive medicines off-label

Nearly four out of five hospitalized children receive medications that have been tested and approved only for adults, according to a study of hundreds of thousands of patient records. This so-called “off-label” use of drugs was thought to be especially common in children, and the new research, the largest-ever U.S. pediatric study, confirms this.

Heart Disease :: Painkillers raise heart disease risk

Many doctors should change the way they prescribe pain relievers for chronic pain in patients with or at risk for heart disease based on accumulated evidence that nonsteroidal anti-inflammatory drugs (NSAIDs), with the exception of aspirin, increase risk for heart attack and stroke, according to an American Heart Association statement published in Circulation: Journal of the American Heart Association.

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