Osteosarcoma :: IDM Pharma’s Mepact, mifamurtide – Junovan in the Treatment of Osteosarcoma

IDM Pharma (NASDAQ:IDMI) announced today that the company has submitted a Marketing Authorization Application (MAA) in eCTD format (electronic common technical document) to the European Medicines Agency (EMEA) for Mepact (mifamurtide for injection), requesting approval for its use in the treatment of patients with newly diagnosed resectable high-grade osteosarcoma following surgical resection in combination with post-operative multi-agent chemotherapy. This announcement follows the October 25, 2006 submission of a New Drug Application (NDA) for Junovan (mifamurtide for injection) to the Food and Drug Administration (FDA) in the United States.

Leukemia :: When Gleevec is not enough

Researchers at the Jackson Laboratory, in collaboration with scientists at Bristol-Myers Squibb Oncology, discovered is that imatinib does not inactivate all BCR-ABL signaling pathways in the cascade. Proteins called SRC kinases are still activated by BCR-ABL in imatinib-treated mouse leukemic cells. Treatment with dasatinib, which inhibits the SRC proteins as well as BCR-ABL, was not only more effective for CML, but also led to complete B-ALL remission.

Cancer :: Philips introduces new MR simulator and CT applications

Royal Philips (NYSE: PHG, AEX: PHI) is introducing advances in its portfolio of leading oncology solutions to help physicians define their targets easily and effectively. Recognizing that console time is at a premium in busy imaging centers, Philips is announcing the availability of its Tumor LOC application on the workstation. The company is also unveiling Panorama 1.0T R/T?the first high field open MR simulator. These technologies are on display at the 48th annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Philadelphia.

Cancer :: ‘Hair Again’ Gives Cancer Journey Meaning

“Medicine alone is not enough to get you through cancer,” comments Linda Dibblee, breast cancer survivor and winner of the 2006 Lilly Oncology on Canvas International Art Competition and Exhibition. “You have to stay strong and positive through even the darkest times. Having a channel through which you can release your feelings can help you find strength that you never knew you had. For me, painting became my way of expressing all my thoughts, hopes and frustrations, and I truly believe it played a part in helping me beat cancer.”

Diabetes :: Accurate coding is key to preventing potentially serious health complications associated with insulin overdose

Significant errors in insulin dose can result when blood glucose meters are miscoded according to new clinical study. When persons with diabetes use miscoded blood glucose meters to determine how much insulin to take, significant errors in insulin dose can result that may potentially lead to short- and long-term health complications, according to findings of a new study presented at the Sixth Annual Diabetes Technology Meeting in Atlanta, Georgia.

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