Genome :: New Leishmania genome sequences highlight gene targets for treatment development

A comparison of three parasite species that cause Leishmaniasis has identified a small number of genes, many new to biology, that will provide a framework to target the search for new treatments. Leishmaniasis is a devastating disease that affects about two million people each year and threatens one-fifth of the world’s population and new treatments are desperately needed.

Meningitis :: Hot on the TRAIL of controlling inflammation in bacterial meningitis

In a study appearing online on June 14 in advance of publication in the July print issue of the Journal of Clinical Investigation, researchers at Charit?-Universit?tsmedizin Berlin report that the molecule known as TRAIL can limit excessive immune responses in bacterial meningitis, and as such may be of use to control inflammation of the spinal cord and brain, which causes brain cell death in this life-threatening disease.

Bacteria :: Deprived bacteria grow up meaner

If the Listeria monocytogenes bacteria behind food poisoning are starved of oxygen, they are liable to turn really nasty according to research published today in the online journal BMC Microbiology. Limiting oxygen produces bacteria up to 100 times more invasive than similar bacteria grown with ample oxygen supplies.

Immunity :: Newly found sensing system enables certain bacteria to resist human immune defenses

Researchers at the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health, have discovered a survival mechanism in a common type of bacteria that can cause illness. The mechanism lets the bacteria protect itself by warding off attacks from antimicrobial peptides (AMPs), which are defense molecules sent by the body to kill bacteria.

Video Game :: Video game helps teens fight their cancer

HopeLab validated the benefits of their cancer-fighting video game by conducting a randomized, controlled trial with 375 male and female cancer patients aged 13 – 29, enrolled at 34 medical centers in the U.S., Canada and Australia.

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