Epilepsy :: Reports of seizure frequency may be inaccurate in patients with focal epilepsy

Asking patients with focal epilepsy (also known as partial seizures, which usually involve focal areas of the body and altered consciousness) how often they have seizures does not appear to provide an accurate count, according to a report in the November issue of Archives of Neurology, one of the JAMA/Archives journals. Reminding patients to record their seizures in a diary may not help, because patients may be unaware of some seizures.

Epilepsy :: Research shows how genetic mutation causes epilepsy in infants

New research from the Howard Florey Institute in Melbourne has shown why mutation in a single gene can cause epilepsy in infants. Infants are more susceptible to seizures because their brains are developing at a rapid rate, making their brain cells ‘excitable’. Their neurons are growing and making new connections with other nerve cells, which can disrupt normal brain activity and results in epilepsy.

Epilepsy :: Ovation further advances development pipeline with new phase III epilepsy study

OVATION Pharmaceuticals, Inc. announced the initiation of a pivotal Phase III clinical trial evaluating clobazam, a unique 1,5 benzodiazapine with significant anticonvulsant properties, as adjunctive treatment for patients with Lennox-Gastaut syndrome (LGS), one of the most severe forms of childhood epilepsy that frequently persists into adulthood.

Epilepsy :: Experiencing auras? You may be a good candidate for epilepsy surgery

People with epilepsy who experience multiple auras, sensations such as a cold breeze or bright light before they have a seizure, may be good candidates for epilepsy surgery because their seizures seem to be coming from one area of the brain, according to a study published in the Aug. 21, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

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